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Symbol
Name
ID
Pten
phosphatase and tensin homolog
MGI:109583
Phenotype annotations related to adipose tissue
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Subcutaneous lipoma
Lipoma
Multiple lipomas
Disease(s) Associated with PTEN
Bannayan-Riley-Ruvalcaba syndrome
macrocephaly-autism syndrome

Mouse Phenotypes
adipose tissue phenotype
abnormal adipose tissue morphology
decreased total body fat amount
decreased body fat mass
abnormal brown adipose tissue morphology
decreased brown fat cell lipid droplet size
decreased white fat cell size
decreased epididymal fat pad weight
increased adipocyte glucose uptake
abnormal brown adipose tissue physiology
Availability Mouse Genotype
Tg(Pten)1Srn/0
Ptentm1Hwu/Ptentm1Hwu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Fabp4-cre)1Abel/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory